ORIA phase I/II study was done to determine safety
Rapamycin also inhibited the multiplication of colony-forming cells in suspension cultures containing IL-3 plus interleukin-1 (IL-1) or interleukin-11 (IL-11) plus KL.read more...
FTY720(fingolimod) is a potent sphingosine-1-phosphate (S1P) receptors agonist with IC50 of 0.137, 10.98 nM for (S)- and (R)- FTY720-phosphate, respectively and reverses the effects of BCR-ABL kinase.know more...
Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine.PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutant BRAF.more details...
Poly (ADP-ribose) polymerase (PARP inhibitor) comprises 17 members (10 putative).PARP inhibitors are essential in the repair of single-stranded breaks in DNA.more info...
RAD001 inhibits the proliferation of a wide variety of human solid tumor cell lines both in vitro in cell culture and in vivo in animal xenograft models.know better...
A phase I/II study was done to determine safety and efficacy of Everolimus in patients with relapsed or refractory hematologic malignancies.
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